Protein name:
Toll-like receptor 2 ;
Alternative:
CD:
CD282 ;
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Interacts with LY96, TLR1 and TLR6 (via extracellular domain). Binds MYD88 (via TIR domain). Interacts with TICAM1. Ligand binding induces the formation of a heterodimer with TLR1 (By similarity). Interacts with CNPY3.
Function:
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MPRALWTAWV | WAVIILSTEG | ASDQASSLSC | DPTGVCDGHS | RSLNSIPSGL |
100:
TAGVKSLDLS | NNDITYVGNR | DLQRCVNLKT | LRLGANEIHT | VEEDSFFHLR |
150:
NLEYLDLSYN | RLSNLSSSWF | RSLYVLKFLN | LLGNLYKTLG | ETSLFSHLPN |
200:
LRTLKVGNSN | SFTEIHEKDF | TGLTFLEELE | ISAQNLQIYV | PKSLKSIQNI |
250:
SHLILHLKQP | ILLVDILVDI | VSSLDCFELR | DTNLHTFHFS | EASISEMSTS |
300:
VKKLIFRNVQ | FTDESFVEVV | KLFNYVSGIL | EVEFDDCTHD | GIGDFRALSL |
350:
DRIRHLGNVE | TLTIRKLHIP | QFFLFHDLSS | IYPLTGRVKR | VTIENSKVFL |
400:
VPCLLSQHLK | SLEYLDLSEN | LMSEETLKNS | ACKDAWPFLQ | TLVLRQNRLK |
450:
SLEKTGELLL | TLENLNNLDI | SKNNFLSMPE | TCQWPGKMKQ | LNLSSTRIHS |
500:
LTQCLPQTLE | ILDVSNNNLD | SFSLILPQLK | ELYISRNKLK | TLPDASFLPV |
550:
LSVMRISRNI | INTFSKEQLD | SFQQLKTLEA | GGNNFICSCD | FLSFTQGQQA |
600:
LGRVLVDWPD | DYRCDSPSHV | RGQRVQDARL | SLSECHRAAV | VSAACCALFL |
650:
LLLLTGVLCH | RFHGLWYMKM | MWAWLQAKRK | PRKAPRRDIC | YDAFVSYSER |
700:
DSYWVENLMV | QELEHFNPPF | KLCLHKRDFI | PGKWIIDNII | DSIEKSHKTI |
750:
FVLSENFVKS | EWCKYELDFS | HFRLFDENND | AAILILLEPI | DKKAIPQRFC |
784:
KLRKIMNTKT | YLEWPVDETQ | QEGFWLNLRA | AIRS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Dog
Bovine
ELISA Kit for Bovine Toll-like receptor 2
ELISA Kit for Bovine Toll-like receptor 2
ELISA Kit for Bovine Toll-like receptor 2
ELISA Kit for Bovine Toll-like receptor 2
CLIA Kit for Bovine Toll-like receptor 2
CLIA Kit for Bovine Toll-like receptor 2
CLIA Kit for Bovine Toll-like receptor 2
CLIA Kit for Bovine Toll-like receptor 2
Polyclonal Antibody for Bovine Toll-like receptor 2
Polyclonal Antibody for Bovine Toll-like receptor 2
Polyclonal Antibody for Bovine Toll-like receptor 2
Polyclonal Antibody for Bovine Toll-like receptor 2
Monoclonal Antibody for Bovine Toll-like receptor 2
Monoclonal Antibody for Bovine Toll-like receptor 2
Monoclonal Antibody for Bovine Toll-like receptor 2
Monoclonal Antibody for Bovine Toll-like receptor 2
Protein for Bovine Toll-like receptor 2
Protein for Bovine Toll-like receptor 2
Protein for Bovine Toll-like receptor 2
Protein for Bovine Toll-like receptor 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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Citations
[1].
Bin Yang, Yifen Zhang, Liuhua Zhou, Zeyu Sun,Junhua Zheng, Yun Chen, and Yutian Dai,
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS GLU-290 AND LYS-783
strain :
Isolate 44 .
strain :
Isolate 74 .
strain :
Isolate 80 .
strain :
Isolate JEW38 .